At Ketamine Lab, one of the most common questions we hear from patients is: “I’m already taking X medication — is it safe to combine it with ketamine?” This is an important question. While ketamine has shown great promise for treatment-resistant depression, anxiety, PTSD, and chronic pain, it does interact in meaningful ways with other medications. Understanding these interactions helps you stay safe and get the best possible results from your sessions. Why Interactions Matter Ketamine affects brain chemistry, blood pressure, and perception. Other medications may either: That’s why we encourage all patients to be open about every prescription, over-the-counter medicine, and supplement they use. Common Drug Categories and Their Considerations ⚠️ Important: This information is for educational purposes only and does not replace medical advice. Always discuss your specific medication list with a qualified clinician. 1. Antidepressants (SSRIs, SNRIs, TCAs, MAOIs) 2. Benzodiazepines (e.g., Xanax, Ativan, Klonopin) 3. Stimulants (e.g., Adderall, Vyvanse, Ritalin) 4. Alcohol, Cannabis, and Other Sedatives 5. Mood Stabilizers and Antipsychotics 6. Antibiotics 7. Supplements That May Reduce Ketamine’s Effectiveness What to Tell Your Doctor Before Starting Ketamine Before your first treatment, bring a complete and honest list of: Being transparent allows your provider to anticipate possible interactions, adjust dosing or timing, and keep you as safe and comfortable as possible. How We Keep You Safe At Ketamine Lab, we: Bottom Line The answer to “Is my medication safe with ketamine?” is rarely a simple yes or no.It depends on the specific drug, your health history, and your treatment goals. The safest approach is to bring your complete medication list to your consultation. We’ll guide you on whether you can continue, need to adjust timing, or should consider alternative strategies.